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In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme
Small self-cleaving nucleolytic ribozymes contain catalytic domains that accelerate site-specific cleavage/ligation of phosphodiester backbones. We report on the 2.9-Å crystal structure of the env22 twister ribozyme, which adopts a compact tertiary fold stabilized by co-helical stacking, double-pseu...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4373348/ https://ncbi.nlm.nih.gov/pubmed/25410397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6534 |
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