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Histone Deacetylase Inhibitors in Clinical Studies as Templates for New Anticancer Agents
Histone dacetylases (HDACs) are a group of enzymes that remove acetyl groups from histones and regulate expression of tumor suppressor genes. They are implicated in many human diseases, especially cancer, making them a promising therapeutic target for treatment of the latter by developing a wide var...
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| Publicado en: | Molecules |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372801/ https://ncbi.nlm.nih.gov/pubmed/25738536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20033898 |
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