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Design, synthesis and evaluation of belinostat analogs as histone deacetylase inhibitors
AIM: Histone deacetylase (HDAC) is an attractive target for antitumor therapy. Therefore, the development of novel HDAC inhibitors is warranted. MATERIALS & METHODS: A series of HDAC inhibitors based on N-hydroxycinnamamide fragment was designed as the clinically used belinostat analog using ami...
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| Udgivet i: | Future Med Chem |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Newlands Press Ltd
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7607388/ https://ncbi.nlm.nih.gov/pubmed/31702394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0587 |
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