Nanoparticles for urothelium penetration and delivery of the histone deacetylase inhibitor belinostat for treatment of bladder cancer

Nearly 40% of patients with non-invasive bladder cancer will progress to invasive disease despite locally-directed therapy. Overcoming the bladder permeability barrier (BPB) is a challenge for intravesical drug delivery. Using the fluorophore coumarin (C6), we synthesized C6-loaded poly(lactide-co-g...

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Detalhes bibliográficos
Main Authors: Martin, Darryl T., Hoimes, Christopher J., Kaimakliotis, Hristos Z., Cheng, Christopher J., Zhang, Ke, Liu, Jingchun, Wheeler, Marcia A., Kelly, W. Kevin, Tew, Greg N., Saltzman, W. Mark, Weiss, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815967/
https://ncbi.nlm.nih.gov/pubmed/23764660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2013.05.017
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