Surface modified nanoparticles enhance transurothelial penetration and delivery of survivin siRNA in treating bladder cancer

Penetration of the bladder permeability barrier (BPB) is a major challenge when treating bladder diseases via intravesical delivery. To increase transurothelial migration and tissue and tumor cell uptake, poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) were modified by addition of a low mol...

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Detalhes bibliográficos
Main Authors: Martin, Darryl T., Steinbach, Jill M., Liu, Jingchun, Shimizu, Shogo, Kaimakliotis, Hristos Z., Wheeler, Marcia A., Hittelman, Adam B., Saltzman, W. Mark, Weiss, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924597/
https://ncbi.nlm.nih.gov/pubmed/24222663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0502
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