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Enhanced siRNA delivery into cells by exploiting the synergy between targeting ligands and cell-penetrating peptides

We have developed a polymer nanoparticle-based siRNA delivery system that exploits a cell-surface binding synergism between targeting ligands and cell-penetrating peptides. Nanoparticles were coated with folate and penetratin via a PEGylated phospholipid linker (DSPE-PEG): the combination of both of...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Cheng, Christopher J, Saltzman, W. Mark
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130098/
https://ncbi.nlm.nih.gov/pubmed/21664689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.04.053
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