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Peptide-Ligand Binding Modeling of siRNA with Cell-Penetrating Peptides
The binding affinity of a series of cell-penetrating peptides (CPP) was modeled through docking and making use of the number of intermolecular hydrogen bonds, lipophilic contacts, and the number of sp3 molecular orbital hybridization carbons. The new ranking of the peptides is consistent with the ex...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Hindawi Publishing Corporation
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131515/ https://ncbi.nlm.nih.gov/pubmed/25147791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/257040 |
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