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Peptide-Ligand Binding Modeling of siRNA with Cell-Penetrating Peptides

The binding affinity of a series of cell-penetrating peptides (CPP) was modeled through docking and making use of the number of intermolecular hydrogen bonds, lipophilic contacts, and the number of sp3 molecular orbital hybridization carbons. The new ranking of the peptides is consistent with the ex...

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Detalhes bibliográficos
Main Authors: García-Sosa, Alfonso T., Tulp, Indrek, Langel, Kent, Langel, Ülo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131515/
https://ncbi.nlm.nih.gov/pubmed/25147791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/257040
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