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Enhanced siRNA delivery into cells by exploiting the synergy between targeting ligands and cell-penetrating peptides
We have developed a polymer nanoparticle-based siRNA delivery system that exploits a cell-surface binding synergism between targeting ligands and cell-penetrating peptides. Nanoparticles were coated with folate and penetratin via a PEGylated phospholipid linker (DSPE-PEG): the combination of both of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3130098/ https://ncbi.nlm.nih.gov/pubmed/21664689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.04.053 |
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