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Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics

BACKGROUND: The Wnt signaling pathway involves secreted glycoproteins that bind to the Frizzled family receptors to activate intracellular signal transduction events that regulate cell proliferation, apoptosis, cell migration and many critical aspects of developmental biology. DISCUSSION: Aberrant W...

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Bibliografiske detaljer
Udgivet i:Future Med Chem
Main Authors: Zheng, Shilong, Liu, Jiawang, Wu, Yanyuan, Huang, Tien L, Wang, Guangdi
Format: Artigo
Sprog:Inglês
Udgivet: Future Science Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810846/
https://ncbi.nlm.nih.gov/pubmed/26670195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.15.159
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