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Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics

BACKGROUND: The Wnt signaling pathway involves secreted glycoproteins that bind to the Frizzled family receptors to activate intracellular signal transduction events that regulate cell proliferation, apoptosis, cell migration and many critical aspects of developmental biology. DISCUSSION: Aberrant W...

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Detalhes bibliográficos
Publicado no:Future Med Chem
Main Authors: Zheng, Shilong, Liu, Jiawang, Wu, Yanyuan, Huang, Tien L, Wang, Guangdi
Formato: Artigo
Idioma:Inglês
Publicado em: Future Science Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810846/
https://ncbi.nlm.nih.gov/pubmed/26670195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.15.159
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