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Chromosome substitution strain assessment of a Huntington’s disease modifier locus
Huntington’s disease (HD) is a dominant neurodegenerative disorder that is due to expansion of an unstable HTT CAG repeat for which genome-wide genetic scans are now revealing chromosome regions that contain disease-modifying genes. We have explored a novel human–mouse cross-species functional prior...
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出版年: | Mamm Genome |
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主要な著者: | , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Springer US
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372682/ https://ncbi.nlm.nih.gov/pubmed/25645993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-014-9552-9 |
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