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Chromosome substitution strain assessment of a Huntington’s disease modifier locus
Huntington’s disease (HD) is a dominant neurodegenerative disorder that is due to expansion of an unstable HTT CAG repeat for which genome-wide genetic scans are now revealing chromosome regions that contain disease-modifying genes. We have explored a novel human–mouse cross-species functional prior...
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| Publicado no: | Mamm Genome |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372682/ https://ncbi.nlm.nih.gov/pubmed/25645993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-014-9552-9 |
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