A modifier of Huntington's disease onset at the MLH1 locus

Huntington's disease (HD) is a dominantly inherited neurodegenerative disease caused by an expanded CAG repeat in HTT. Many clinical characteristics of HD such as age at motor onset are determined largely by the size of HTT CAG repeat. However, emerging evidence strongly supports a role for oth...

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Bibliographische Detailangaben
Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Lee, Jong-Min, Chao, Michael J., Harold, Denise, Abu Elneel, Kawther, Gillis, Tammy, Holmans, Peter, Jones, Lesley, Orth, Michael, Myers, Richard H., Kwak, Seung, Wheeler, Vanessa C., MacDonald, Marcy E., Gusella, James F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Association Studies Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455020/
https://ncbi.nlm.nih.gov/pubmed/28934397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx286
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