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HIV enhancing activity of semen impairs the antiviral efficacy of microbicides

Topically applied microbicides potently inhibit HIV in vitro but have largely failed to exert protective effects in clinical trials. One possible reason for this discrepancy is that the preclinical testing of microbicides does not faithfully reflect the conditions of HIV sexual transmission. Here, w...

詳細記述

保存先:
書誌詳細
出版年:Sci Transl Med
主要な著者: Zirafi, Onofrio, Kim, Kyeong-Ae, Roan, Nadia R., Kluge, Silvia F., Müller, Janis A., Jiang, Shibo, Mayer, Benjamin, Greene, Warner C., Kirchhoff, Frank, Münch, Jan
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372245/
https://ncbi.nlm.nih.gov/pubmed/25391483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009634
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