Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI

BACKGROUND: HIV-1 is usually transmitted in the presence of semen. We have shown that semen boosts HIV-1 infection and contains fragments of prostatic acid phosphatase (PAP) forming amyloid aggregates termed SEVI (semen-derived enhancer of viral infection) that promote virion attachment to target ce...

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Bibliografiske detaljer
Main Authors: Kim, Kyeong-Ae, Yolamanova, Maral, Zirafi, Onofrio, Roan, Nadia R, Staendker, Ludger, Forssmann, Wolf-Georg, Burgener, Adam, Dejucq-Rainsford, Nathalie, Hahn, Beatrice H, Shaw, George M, Greene, Warner C, Kirchhoff, Frank, Münch, Jan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914040/
https://ncbi.nlm.nih.gov/pubmed/20573198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-55
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