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Naturally Occurring Fragments from Two Distinct Regions of the Prostatic Acid Phosphatase Form Amyloidogenic Enhancers of HIV Infection

Semen is the major vector for HIV-1 transmission. We previously isolated C-proximal fragments of the prostatic acid phosphatase (PAP) from semen which formed amyloid fibrils that potently enhanced HIV infection. Here, we used the same methodology and identified another amyloidogenic peptide. Surpris...

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Autors principals: Arnold, Franziska, Schnell, Jacqueline, Zirafi, Onofrio, Stürzel, Christina, Meier, Christoph, Weil, Tanja, Ständker, Ludger, Forssmann, Wolf-Georg, Roan, Nadia R., Greene, Warner C., Kirchhoff, Frank, Münch, Jan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255800/
https://ncbi.nlm.nih.gov/pubmed/22090109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06121-11
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