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A Fibrinogen Alpha Fragment Mitigates Chemotherapy-Induced MLL Rearrangements
Rearrangements in the Mixed Lineage Leukemia breakpoint cluster region (MLLbcr) are frequently involved in therapy-induced leukemia, a severe side effect of anti-cancer therapies. Previous work unraveled Endonuclease G as the critical nuclease causing initial breakage in the MLLbcr in response to di...
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| 發表在: | Front Oncol |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8249925/ https://ncbi.nlm.nih.gov/pubmed/34222016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.689063 |
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