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Leukemogenic rearrangements at the mixed lineage leukemia gene (MLL)—multiple rather than a single mechanism
Despite manifold efforts to achieve reduced-intensity and -toxicity regimens, secondary leukemia has remained the most severe side effect of chemotherapeutic cancer treatment. Rearrangements involving a short telomeric <1 kb region of the mixed lineage leukemia (MLL) gene are the most frequently...
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| Publié dans: | Front Cell Dev Biol |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479792/ https://ncbi.nlm.nih.gov/pubmed/26161385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2015.00041 |
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