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Preferential induction of MLL(Mixed Lineage Leukemia) rearrangements in human lymphocyte cultures treated with etoposide

Topoisomerase II inhibitors are effective chemotherapeutic agents in the treatment of cancer, in spite of being associated with the development of secondary leukemia. Our purpose was to determine the effects of etoposide on different genomic regions, aiming at discovering whether there are preferent...

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Bibliografiska uppgifter
Huvudupphovsmän: Brassesco, María Sol, Montaldi, Ana Paula, Sakamoto-Hojo, Elza Tiemi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Sociedade Brasileira de Genética 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032972/
https://ncbi.nlm.nih.gov/pubmed/21637660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-47572009000100022
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