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The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia
Leukemia phenotypes vary with age of onset. Delineating mechanisms of age specificity in leukemia could improve disease models and uncover new therapeutic approaches. Here, we used heterochronic transplantation of leukemia driven by MLL/KMT2A translocations to investigate the contribution of the age...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400531/ https://ncbi.nlm.nih.gov/pubmed/30728174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181765 |
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