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Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes

A number of acute leukemias arise from fusion of the mixed lineage leukemia 1 protein (MLL) N terminus to a variety of fusion partners that have been reported to reside in one or more poorly defined complexes linked to transcription elongation through interactions with the histone H3-K79 methyltrans...

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Hlavní autoři: Biswas, Debabrata, Milne, Thomas A., Basrur, Venkatesha, Kim, Jaehoon, Elenitoba-Johnson, Kojo S. J., Allis, C. David, Roeder, Robert G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179097/
https://ncbi.nlm.nih.gov/pubmed/21896721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111498108
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