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HIV enhancing activity of semen impairs the antiviral efficacy of microbicides
Topically applied microbicides potently inhibit HIV in vitro but have largely failed to exert protective effects in clinical trials. One possible reason for this discrepancy is that the preclinical testing of microbicides does not faithfully reflect the conditions of HIV sexual transmission. Here, w...
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| Veröffentlicht in: | Sci Transl Med |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372245/ https://ncbi.nlm.nih.gov/pubmed/25391483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3009634 |
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