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New Inhibitor of 3-Phosphoinositide Dependent Protein Kinase-1 Identified from Virtual Screening
3-Phosphoinositide-dependent protein kinase-1 (PDK1) has been recognized as a promising anticancer target. Thus, it is interesting to identify new inhibitors of PDK1 for anticancer drug discovery. Through a combined use of virtual screening and wet experimental activity assays, we have identified a...
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| Pubblicato in: | Bioorg Med Chem Lett |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371734/ https://ncbi.nlm.nih.gov/pubmed/22266037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.12.121 |
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