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Teaching an Old Dog New Tricks: Strategies That Improve Early Recognition in Similarity-Based Virtual Screening

High throughput screening (HTS) is an important component of lead discovery, with virtual screening playing an increasingly important role. Both methods typically suffer from lack of sensitivity and specificity against their true biological targets. With ever-increasing screening libraries and virtu...

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Bibliografiske detaljer
Udgivet i:Front Chem
Main Authors: Liu, Ruifeng, AbdulHameed, Mohamed Diwan M., Wallqvist, Anders
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819673/
https://ncbi.nlm.nih.gov/pubmed/31709231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00701
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