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Novel Mycosin Protease MycP(1) Inhibitors Identified by Virtual Screening and 4D Fingerprints
[Image: see text] The rise of drug-resistant Mycobacterium tuberculosis lends urgency to the need for new drugs for the treatment of tuberculosis (TB). The identification of a serine protease, mycosin protease-1 (MycP(1)), as the crucial agent in hydrolyzing the virulence factor, ESX-secretion-assoc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010288/ https://ncbi.nlm.nih.gov/pubmed/24628123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci500025r |
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