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Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence
Mycobacterium tuberculosis uses the ESX-1 secretion system to deliver virulence proteins during infection of host cells. Here we report a novel post-transcriptional control mechanism of ESX-1 mediated by MycP1, a serine protease. We show that MycP1 is required for ESX-1 secretion and has unusual sub...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3121311/ https://ncbi.nlm.nih.gov/pubmed/20227664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.02.006 |
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