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Novel human mPGES-1 inhibitors identified through structure-based virtual screening
Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible prostaglandin E synthase after exposure to pro-inflammatory stimuli and, therefore, represents a novel target for therapeutic treatment of acute and chronic inflammatory disorders. It is essential to identify mPGES-1 inhibitors with nov...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183289/ https://ncbi.nlm.nih.gov/pubmed/21920764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.08.040 |
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