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Novel human mPGES-1 inhibitors identified through structure-based virtual screening

Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible prostaglandin E synthase after exposure to pro-inflammatory stimuli and, therefore, represents a novel target for therapeutic treatment of acute and chronic inflammatory disorders. It is essential to identify mPGES-1 inhibitors with nov...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hamza, Adel, Zhao, Xinyun, Tong, Min, Tai, Hsin-Hsiung, Zhan, Chang-Guo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183289/
https://ncbi.nlm.nih.gov/pubmed/21920764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.08.040
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