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Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway
Programmed −1 ribosomal frameshift (−1 PRF) signals redirect translating ribosomes to slip back one base on messenger RNAs. Although well characterized in viruses, how these elements may regulate cellular gene expression is not understood. Here we describe a −1 PRF signal in the human mRNA encoding...
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| Vydáno v: | Nature |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369343/ https://ncbi.nlm.nih.gov/pubmed/25043019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13429 |
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