Endogenous ribosomal frameshift signals operate as mRNA destabilizing elements through at least two molecular pathways in yeast

Although first discovered in viruses, previous studies have identified operational −1 ribosomal frameshifting (−1 RF) signals in eukaryotic genomic sequences, and suggested a role in mRNA stability. Here, four yeast −1 RF signals are shown to promote significant mRNA destabilization through the nons...

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Detaylı Bibliyografya
Asıl Yazarlar: Belew, Ashton T., Advani, Vivek M., Dinman, Jonathan D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2011
Konular:
RNA
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074144/
https://ncbi.nlm.nih.gov/pubmed/21109528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1220
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