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Cell cycle control (and more) by programmed −1 ribosomal frameshifting: implications for disease and therapeutics

Like most basic molecular mechanisms, programmed –1 ribosomal frameshifting (−1 PRF) was first identified in viruses. Early observations that global dysregulation of −1 PRF had deleterious effects on yeast cell growth suggested that −1 PRF may be used to control cellular gene expression, and the cel...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Belew, Ashton T, Dinman, Jonathan D
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615106/
https://ncbi.nlm.nih.gov/pubmed/25584829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.989123
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