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Single-Molecule Measurements of the CCR5 mRNA Unfolding Pathways

Secondary or tertiary structure in an mRNA, such as a pseudoknot, can create a physical barrier that requires the ribosome to generate additional force to translocate. The presence of such a barrier can dramatically increase the probability that the ribosome will shift into an alternate reading fram...

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Detalles Bibliográficos
Main Authors: de Messieres, Michel, Chang, Jen-Chien, Belew, Ashton Trey, Meskauskas, Arturas, Dinman, Jonathan D., La Porta, Arthur
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907219/
https://ncbi.nlm.nih.gov/pubmed/24411256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.09.036
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