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DISSECTING STRUCTURAL AND ELECTRONIC EFFECTS IN INDUCIBLE NITRIC OXIDE SYNTHASE

Nitric oxide synthases (NOS) are haem-thiolate enzymes that catalyse the conversion of L-Arginine (LArg) into NO and citrulline. Inducible NOS (iNOS) is responsible for delivery of NO in response to stressors during inflammation. The catalytic performance of iNOS is proposed to rely mainly on the ha...

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Détails bibliographiques
Publié dans:Biochem J
Auteurs principaux: Hannibal, Luciana, Page, Richard C., Haque, Mohammad Mahfuzul, Bolisetty, Karthik, Yu, Zhihao, Misra, Saurav, Stuehr, Dennis J.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369157/
https://ncbi.nlm.nih.gov/pubmed/25608846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141319
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