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DISSECTING STRUCTURAL AND ELECTRONIC EFFECTS IN INDUCIBLE NITRIC OXIDE SYNTHASE

Nitric oxide synthases (NOS) are haem-thiolate enzymes that catalyse the conversion of L-Arginine (LArg) into NO and citrulline. Inducible NOS (iNOS) is responsible for delivery of NO in response to stressors during inflammation. The catalytic performance of iNOS is proposed to rely mainly on the ha...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Hannibal, Luciana, Page, Richard C., Haque, Mohammad Mahfuzul, Bolisetty, Karthik, Yu, Zhihao, Misra, Saurav, Stuehr, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369157/
https://ncbi.nlm.nih.gov/pubmed/25608846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141319
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