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Surface Charges and Regulation of FMN to Heme Electron Transfer in Nitric-oxide Synthase
The nitric-oxide synthases (NOS, EC 1.14.13.39) are modular enzymes containing attached flavoprotein and heme (NOSoxy) domains. To generate nitric oxide (NO), the NOS FMN subdomain must interact with the NOSoxy domain to deliver electrons to the heme for O(2) activation during catalysis. The molecul...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930722/ https://ncbi.nlm.nih.gov/pubmed/20592038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138842 |
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