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Fast Ferrous Heme-NO Oxidation in Nitric Oxide Synthases
During catalysis, the heme in nitric oxide synthase (NOS) binds NO before releasing it to the environment. Oxidation of the NOS ferrous heme-NO complex by O(2) is key for catalytic cycling, but the mechanism is unclear. We utilized stopped-flow methods to study reaction of O(2) with ferrous heme-NO...
Kaydedildi:
| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737443/ https://ncbi.nlm.nih.gov/pubmed/19691141 |
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