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Surface Charges and Regulation of FMN to Heme Electron Transfer in Nitric-oxide Synthase

The nitric-oxide synthases (NOS, EC 1.14.13.39) are modular enzymes containing attached flavoprotein and heme (NOSoxy) domains. To generate nitric oxide (NO), the NOS FMN subdomain must interact with the NOSoxy domain to deliver electrons to the heme for O(2) activation during catalysis. The molecul...

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Bibliografiska uppgifter
Huvudupphovsmän: Tejero, Jesús, Hannibal, Luciana, Mustovich, Anthony, Stuehr, Dennis J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930722/
https://ncbi.nlm.nih.gov/pubmed/20592038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138842
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