Carrier-Mediated Cocaine Transport at the Blood-Brain Barrier as a Putative Mechanism in Addiction Liability

BACKGROUND: The rate of entry of cocaine into the brain is a critical factor that influences neuronal plasticity and the development of cocaine addiction. Until now, passive diffusion has been considered the unique mechanism known by which cocaine crosses the blood-brain barrier. METHODS: We reasses...

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Vydáno v:Int J Neuropsychopharmacol
Hlavní autoři: Chapy, Hélène, Smirnova, Maria, André, Pascal, Schlatter, Joël, Chiadmi, Fouad, Couraud, Pierre-Olivier, Scherrmann, Jean-Michel, Declèves, Xavier, Cisternino, Salvatore
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368859/
https://ncbi.nlm.nih.gov/pubmed/25539501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu001
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