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A polyspecific drug/proton antiporter mediates diphenhydramine and clonidine transport at the mouse blood-retinal barrier

BACKGROUND AND PURPOSE: Transporters at the blood-retinal barrier (BRB), as at the blood–brain barrier (BBB), regulate the distribution of compounds into the neural parenchyma. However, the expression of BRB transporters and their quantitative impact in vivo are still poorly understood. EXPERIMENTAL...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Chapy, Hélène, André, Pascal, Declèves, Xavier, Scherrmann, Jean-Michel, Cisternino, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594274/
https://ncbi.nlm.nih.gov/pubmed/26177775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13246
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