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Coexistence of Passive and Proton Antiporter-Mediated Processes in Nicotine Transport at the Mouse Blood–Brain Barrier

Nicotine, the main tobacco alkaloid leading to smoking dependence, rapidly crosses the blood–brain barrier (BBB) to become concentrated in the brain. Recently, it has been shown that nicotine interacts with some organic cation transporters (OCT), but their influence at the BBB has not yet been asses...

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Detalhes bibliográficos
Main Authors: Cisternino, Salvatore, Chapy, Hélène, André, Pascal, Smirnova, Maria, Debray, Marcel, Scherrmann, Jean-Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675746/
https://ncbi.nlm.nih.gov/pubmed/23212563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9434-6
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