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Protein-Binding RNA Aptamers Affect Molecular Interactions Distantly from Their Binding Sites

Nucleic acid aptamer selection is a powerful strategy for the development of regulatory agents for molecular intervention. Accordingly, aptamers have proven their diligence in the intervention with serine protease activities, which play important roles in physiology and pathophysiology. Nonetheless,...

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Publicat a:PLoS One
Autors principals: Dupont, Daniel M., Thuesen, Cathrine K., Bøtkjær, Kenneth A., Behrens, Manja A., Dam, Karen, Sørensen, Hans P., Pedersen, Jan S., Ploug, Michael, Jensen, Jan K., Andreasen, Peter A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368798/
https://ncbi.nlm.nih.gov/pubmed/25793507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119207
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