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Protein-Binding RNA Aptamers Affect Molecular Interactions Distantly from Their Binding Sites

Nucleic acid aptamer selection is a powerful strategy for the development of regulatory agents for molecular intervention. Accordingly, aptamers have proven their diligence in the intervention with serine protease activities, which play important roles in physiology and pathophysiology. Nonetheless,...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Dupont, Daniel M., Thuesen, Cathrine K., Bøtkjær, Kenneth A., Behrens, Manja A., Dam, Karen, Sørensen, Hans P., Pedersen, Jan S., Ploug, Michael, Jensen, Jan K., Andreasen, Peter A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368798/
https://ncbi.nlm.nih.gov/pubmed/25793507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119207
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