Glucagon-reactive islet-infiltrating CD8 T cells in NOD mice

Type 1 diabetes is characterized by T-cell-mediated destruction of the insulin-producing β cells in pancreatic islets. A number of islet antigens recognized by CD8 T cells that contribute to disease pathogenesis in non-obese diabetic (NOD) mice have been identified; however, the antigenic specificit...

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Vydáno v:Immunology
Hlavní autoři: Mukherjee, Gayatri, Chaparro, Rodolfo J, Schloss, Jennifer, Smith, Carla, Bando, Christopher D, DiLorenzo, Teresa P
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368169/
https://ncbi.nlm.nih.gov/pubmed/25333865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12415
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