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Efficient culture of CD8(+) T cells from the islets of NOD mice and their use for the study of autoreactive specificities
During progression to type 1 diabetes (T1D), the pancreatic islets of humans and of the widely studied mouse model of T1D, the nonobese diabetic (NOD) mouse, are infiltrated by cells of the immune system. Here we report that infiltrated mouse islets (“translucent islets”) can be identified visually....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596588/ https://ncbi.nlm.nih.gov/pubmed/18782577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2008.08.007 |
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