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Restricted islet-cell reactive T cell repertoire of early pancreatic islet infiltrates in NOD mice
The mechanisms responsible for initiating autoimmune diabetes remain obscure. Here, we describe a method for identifying both the α- and β-chains of the T cell receptor (TCR) from individual pancreatic islet-infiltrating T cells at the earliest stages of disease in nonobese diabetic mice (NOD). Anal...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123148/ https://ncbi.nlm.nih.gov/pubmed/12082183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.142284899 |
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