IFNα signaling through PKC-θ is essential for antitumor NK cell function

We have previously shown that the development of a major histocompatibility complex class I (MHC-I)-deficient tumor was favored in protein kinase C-θ knockout (PKC-θ(−/−)) mice compared to that occurring in wild-type mice. This phenomenon was associated with scarce recruitment of natural killer (NK)...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Comet, Natalia R, Aguiló, Juan Ignacio, Rathoré, Moeez G, Catalán, Elena, Garaude, Johan, Uzé, Gilles, Naval, Javier, Pardo, Julián, Villalba, Martín, Anel, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2014
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368137/
https://ncbi.nlm.nih.gov/pubmed/25960930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.948705
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