ERK5 Knockdown Generates Mouse Leukemia Cells with Low MHC Class I Levels That Activate NK Cells and Block Tumorigenesis

Tumor cell-based vaccines are currently used in clinical trails, but they are in general poorly immunogenic because they are composed of cell extracts or apoptotic cells. Live tumor cells should be much better Ags provided that they are properly processed by the host immune system. We show herein th...

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Publicado en:J Immunol
Main Authors: Charni, Seyma, Aguilo, Juan Ignacio, Garaude, Johan, de Bettignies, Geoffroy, Jacquet, Chantal, Hipskind, Robert A., Singer, Dinah, Anel, Alberto, Villalba, Martin
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311211/
https://ncbi.nlm.nih.gov/pubmed/19265117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803006
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