Identification and Characterization of ML352: A Novel, Noncompetitive Inhibitor of the Presynaptic Choline Transporter

[Image: see text] The high-affinity choline transporter (CHT) is the rate-limiting determinant of acetylcholine (ACh) synthesis, yet the transporter remains a largely undeveloped target for the detection and manipulation of synaptic cholinergic signaling. To expand CHT pharmacology, we pursued a hig...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Ennis, Elizabeth A., Wright, Jane, Retzlaff, Cassandra L., McManus, Owen B., Lin, Zhinong, Huang, Xiaofang, Wu, Meng, Li, Min, Daniels, J. Scott, Lindsley, Craig W., Hopkins, Corey R., Blakely, Randy D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4367188/
https://ncbi.nlm.nih.gov/pubmed/25560927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn5001809
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