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The Presynaptic Choline Transporter Imposes Limits on Sustained Cortical Acetylcholine Release and Attention
Functional variation in the gene encoding the presynaptic choline transporter (CHT) has been linked to attention-deficit/hyperactivity disorder. Here, we report that a heterozygous deletion in the CHT gene in mice (CHT(+/−)) limits the capacity of cholinergic neurons to sustain acetylcholine (ACh) r...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Society for Neuroscience
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711270/ https://ncbi.nlm.nih.gov/pubmed/23392663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4993-12.2013 |
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