The Presynaptic Choline Transporter Imposes Limits on Sustained Cortical Acetylcholine Release and Attention

Functional variation in the gene encoding the presynaptic choline transporter (CHT) has been linked to attention-deficit/hyperactivity disorder. Here, we report that a heterozygous deletion in the CHT gene in mice (CHT(+/−)) limits the capacity of cholinergic neurons to sustain acetylcholine (ACh) r...

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Hlavní autoři: Parikh, Vinay, St. Peters, Megan, Blakely, Randy D., Sarter, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711270/
https://ncbi.nlm.nih.gov/pubmed/23392663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4993-12.2013
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