Differential Impact of Genetically Modulated Choline Transporter Expression on the Release of Endogenous Versus Newly Synthesized Acetylcholine

The efficient import of choline into cholinergic nerve terminals by the presynaptic, high-affinity choline transporter (CHT, SLC5A7) dictates the capacity for acetylcholine (ACh) synthesis and release. Tissue levels of ACh are significantly reduced in mice heterozygous for a loss of function mutatio...

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Vydáno v:Neurochem Int
Hlavní autoři: Iwamoto, Hideki, Calcutt, M. Wade, Blakely, Randy D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969175/
https://ncbi.nlm.nih.gov/pubmed/27013347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2016.03.012
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