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Differential Impact of Genetically Modulated Choline Transporter Expression on the Release of Endogenous Versus Newly Synthesized Acetylcholine
The efficient import of choline into cholinergic nerve terminals by the presynaptic, high-affinity choline transporter (CHT, SLC5A7) dictates the capacity for acetylcholine (ACh) synthesis and release. Tissue levels of ACh are significantly reduced in mice heterozygous for a loss of function mutatio...
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| Veröffentlicht in: | Neurochem Int |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4969175/ https://ncbi.nlm.nih.gov/pubmed/27013347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2016.03.012 |
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